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Talquetamab + Daratumumab Is Well Tolerated in Relapsed/Refractory Multiple Myeloma Patients

by CheckRare Staff | Jan 20, 2022

  Ajai Chari, MD from the Mount Sinai School of Medicine discusses the TRiMM-2 study of teclistamab and talquetamab in combination with daratumumab in the treatment of relapsed/refractory multiple myeloma. Results from this study were recently presented in two...

Treatment Benefit of Daratumumab for Multiple Myeloma Supported by 3-Year Follow-Up Data

by Peter Ciszewski | Jan 19, 2022

  Jacob Laubach, MD at the Dana-Farber Cancer Institute discusses updated safety and efficacy data from the phase 2 GRIFFIN trial assessing daratumumab plus lenalidomide, bortezomib, and dexamethasone in newly diagnosed multiple myeloma patients. The data were...

Albumin-Bound Sirolimus: Newly-Approved Treatment for PEComa

by Peter Ciszewski | Jan 18, 2022

  Brendan Delaney, MBA, Chief Operating Officer of Aadi Bioscience, discusses albumin-bound sirolimus (Fyarro), the recently-approved treatment for malignant perivascular epithelioid cell tumor (PEComa). PEComa is an ultra-rare family of sarcomas. Most PEComa...

MT1621: A Possible Treatment for Thymidine Kinase 2 Deficiency

by CheckRare Staff | Jan 17, 2022

  Bradley Galer, MD, Executive Vice President and Chief Medical Officer, Zogenix, discusses MT1621, an investigational treatment for thymidine kinase 2 deficiency (TK2d). TK2d is an ultra-rare genetic mitochondrial disease characterized by progressive myopathy,...

Current and Emerging Therapies for PKU (Including SYNB1618)

by James Radke, PhD | Jan 14, 2022

  Jerry Vockley, MD, PhD, Head of the Division of Medical Genetics at UPMC Children’s Hospital of Pittsburgh, gives an overview of the treatment landscape for phenylketonuria (PKU), going further into detail about the mechanism of action of SYNB1618, an oral drug...
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