The Role of p53 and MDM2 in Cancer Growth

  Avanish Vellanki, Cofounder and CEO at Rain Therapeutics, discusses the role of p53 and MDM2 in cancers like liposarcoma. As Mr. Vellanki explains, p53 regulates the cell cycle, and in that role is essential for tumor suppression. MDM2 is a crucial regulator of...

Treatment Options for Systemic Mastocytosis

  Daniel DeAngelo, MD, PhD, Chief, Division of Leukemia, Dana-Farber Cancer Institute, discusses treatment options available for systemic mastocytosis (SM). SM is a rare, hematologic disorder most often caused by a mutation in the KIT D816V gene. The disorder is...

Two Things Physicians Ought to Know about CTCL

  Lauren Pinter-Brown, MD, Clinical Professor of Hematology/Oncology, University of California Irvine and Director of the Cutaneous Lymphoma Foundation, discusses what physicians should know about cutaneous T-cell lymphoma (CTCL).  CTCL belongs to the non-Hodgkin...