Jeffrey W Olin, DO is a Professor of Medicine at the Icahn School of Medicine at Mount Sinai and Director of Vascular Medicine and the Vascular Diagnostic Laboratory in the Zena and Michael A. Wiener Cardiovascular Institute and Marie-Josée and Henry R. Kravis Center for Cardiovascular Health of The Mount Sinai Medical Center. In this video, Dr Olin provides an overview of fibromuscular dysplasia (FMD), a rare condition characterized by abnormal development or growth of cells in the walls of blood vessels (arteries) that can cause the vessels to narrow. The carotid arteries, which pass through the neck and supply blood to the brain, are commonly affected. Arteries within the brain and kidneys can also be affected. Some people with FMD experience no symptoms of the disease while others may experience high blood pressure, dizziness or vertigo, chronic headache, ringing in the ears, weakness or numbness in the face, neck pain, or changes in vision. Potential severe complications include arterial aneurysms and dissections, stroke, subarachnoid hemorrhage (when a brain aneurysm ruptures), and mesenteric ischemia.

FMD is most often seen in people age 25 to 50 years and affects women more often than men. The cause of FMD is unknown, however, genetic and hormonal factors may be involved. Familial cases of FMD are rare. Treatment is based on the arteries affected and the progression and severity of the disease.