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Complement-Mediated Kidney Disorders: A Case Series

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Start date: Nov 15, 2024
End date: Nov 15, 2025
Estimated time to complete: 0.75 hours
Physicians: 0.75 AMA PRA Category 1 Credits™

Jointly Provided by American Academy of CME and CheckRare CE

Support for this accredited continuing education activity has been made possible through an educational grant from Novartis

This 45-minute CME-accredited program, developed by Howard Trachtman, MD, FASN, and Carla M. Nester, MD, MSA, FASN, utilizes three unique case studies to address clinical questions which explore the complexities involved in diagnosing, treating, and managing patients with various complement-mediated kidney disorders, such as C3 glomerulopathy and atypical hemolytic uremic syndrome (aHUS).

Target Audience

This activity has been designed to meet the educational needs of physicians specializing in nephrology, pathology, and managed care. Other healthcare providers, including nephrology nurse practitioners, physician assistants, and pharmacists, involved in caring for patients with complement-mediated kidney disorders may also participate.

Learning Objectives

After participating in the activity, learners should be better able to:

  • Explain the importance of genetic testing in aHUS and other complement-mediated kidney disorders.
  • Describe emerging therapies for patients with complement-mediated kidney diseases, including their efficacy and safety.
  • Explain strategies the care team can use to improve the quality of life in patients with complement-mediated kidney diseases.
Howard Trachtman, MD, FASN
Adjunct Professor of Pediatrics
University of Michigan

Carla M. Nester, MD, MSA, FASN
Jean Robillard Professor of Pediatric Nephrology
Division Director of Pediatric Nephrology, Dialysis, and Transplantation
University of Iowa Stead Family Children’s Hospital

Disclosure Statement

According to the disclosure policy of the Academy, all faculty, planning committee members, editors, managers and other individuals who are in a position to control content are required to disclose any relationships with any ineligible company(ies). The existence of these relationships is not viewed as implying bias or decreasing the value of the activity. Clinical content has been reviewed for fair balance and scientific objectivity, and all of the relevant financial relationships listed for these individuals have been mitigated.

Disclosure of relevant financial relationships are as follows:

Faculty Educators/Planners

Dr. Trachtman discloses the following relevant financial relationships with ineligible companies:

  • Consultant: Aclipse, Alexion, Eloxx, Boehringer-Ingelheim, Dimerix, Maze Therapeutics, NephCure, Otsuka, PhaseV, Travere Therapeutics, Walden, ProKidney, Novartis, Vera Therapeutics
  • Shareholder: Aclipse

Dr. Nester discloses the following relevant financial relationships with ineligible companies:

  • Advisory Board: Achillion, Apellis, AstraZeneca-Alexion, Biocryst, Novartis
  • Data Safety Monitoring Board: Kira
  • Grant/Research Support: Achillion, Apellis, Biocryst, Novartis, Retrophin

Planners for this activity have no relevant financial relationships with any ineligible companies.

This activity will review off-label or investigational information.

The opinions expressed in this educational activity are those of the faculty, and do not represent those of the Academy or CheckRare CE. This activity is intended as a supplement to existing knowledge, published information, and practice guidelines. Learners should appraise the information presented critically, and draw conclusions only after careful consideration of all available scientific information.

Accreditation and Credit Designation

In support of improving patient care, this activity has been planned and implemented by American Academy of CME, Inc. and CheckRare CE. American Academy of CME, Inc. is Jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physicians

American Academy of CME, Inc., designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Other HCPs

Other members of the care team will receive a certificate of participation.

There are no fees to participate in the activity.  Participants must review the activity information including the learning objectives and disclosure statements, as well as the content of the activity. To receive CME credit for your participation, please complete the pre and post-program assessments. Your certificate will be emailed to you within 30 days.

Hardware/Software Requirements

Windows Requirements: • Operating system: Windows XP Service Pack 2 or later • Browser: Internet Explorer 7 or later, Mozilla Firefox 2.5 or later • Internet connection: DSL, cable modem, or other high-speed connection

Macintosh Requirements: • Operating system: Mac OS X v10.3 or later • Browser: Mozilla Firefox 2.5 or later • Internet connection: DSL, cable modem, or other high-speed connection

Privacy

For more information about the American Academy of CME privacy policy, please access http://www.academycme.org/privacy.htm  For more information about CheckRare’s privacy policy, please access https://checkrare.com/privacy/

Contact

For any questions, please contact: CEServices@academycme.org

Copyright

© 2024. This CME-certified activity is held as copyrighted © by American Academy of CME and CheckRare CE. Through this notice, the Academy and CheckRare CE grant permission of its use for educational purposes only. These materials may not be used, in whole or in part, for any commercial purposes without prior permission in writing from the copyright owner(s).