Highlights on Pyruvate Kinase (PK) Deficiency from the 2021 American Society of Hematology Annual Meeting
Jointly Provided by
Supported by an educational grant from Agios Pharmaceuticals, Inc.
Start date: February 20, 2022
End date: March 31, 2023
Estimated time to complete: 0.25 hours
NO LONGER AVAILABLE FOR CREDIT
Activity Description
This accredited CME activity provides a summary of the latest information about Pyruvate kinase (PK) deficiency that was presented at the 2021 American Society of Hematology Annual Meeting (ASH 2021). Since the Covid-19 pandemic limited the ability for specialists to attend ASH 2021 and discuss this latest research, this program provides a review by Rachael Grace, MD, of the most clinically-relevant information on PK deficiency presented during the meeting.
PK deficiency is a rare genetic blood disorder characterized by low levels of the enzyme pyruvate kinase, which interrupts the glycolytic pathway causing hemolytic anemia. The degree of hemolysis is variable, ranging from mild forms of PK deficiency to life-threatening neonatal anemia that require exchange transfusions and subsequent continuous transfusion support. Both hematologists and generalists who may be involved in the care of patients with PK deficiency may benefit from learning the latest information about this rare disease, and its implications for patient care.
Activity Faculty
Rachael Grace, MD, MMSc
Associate Professor, Harvard Medical School
Director, Hematology Clinical Research Program
Dana-Farber/Boston Children’s Cancer and Blood Disorders Center
Boston, MA
Target Audience
This activity has been designed to meet the educational needs of physicians specializing in hematology and general medicine/pediatrics. Other members of the care team may also participate.
After participating in the activity, learners should be better able to:
- Describe the latest research to better manage people with PK deficiency and its clinical relevance
Accreditation and Credit Designation
In support of improving patient care, this activity has been planned and implemented by American Academy of CME, Inc. and CheckRare CE. American Academy of CME, Inc. is Jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physicians
American Academy of CME, Inc., designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Disclosure Statement
According to the disclosure policy of the Academy, all faculty, planning committee members, editors, managers and other individuals who are in a position to control content are required to disclose any relationships with any ineligible company(ies). The existence of these relationships is not viewed as implying bias or decreasing the value of the activity. Clinical content has been reviewed for fair balance and scientific objectivity, and all of the relevant financial relationships listed for these individuals have been mitigated.
Disclosures are as follows:
Faculty Educators
Dr. Grace discloses the following financial relationships:
- Advisory Board/Consultant: Agios, Principia
- Grant/Research Support: Agios, Dova, Novartis
Planners for this activity have no relevant financial relationships with any commercial interests.
This activity will review off-label or investigational information (RP-301).
The opinions expressed in this educational activity are those of the faculty, and do not represent those of the Academy or CheckRare CE. This activity is intended as a supplement to existing knowledge, published information, and practice guidelines. Learners should appraise the information presented critically, and draw conclusions only after careful consideration of all available scientific information.
Method of Participation
There are no fees to participate in the activity. Participants must review the activity information including the learning objectives and disclosure statements, as well as the content of the activity. To receive CME credit for your participation, please complete the pre and post-program assessments. Your certificate will be emailed to you in within 30 days.
Hardware/Software Requirements
Windows Requirements: • Operating system: Windows XP Service Pack 2 or later • Browser: Internet Explorer 7 or later, Mozilla Firefox 2.5 or later • Internet connection: DSL, cable modem, or other high-speed connection
Macintosh Requirements: • Operating system: Mac OS X v10.3 or later • Browser: Mozilla Firefox 2.5 or later • Internet connection: DSL, cable modem, or other high-speed connection
Privacy
For more information about the American Academy of CME privacy policy, please access http://www.academycme.org/privacy.htm. For more information about CheckRare’s privacy policy, please access https://checkrare.com/privacy/
Contact
For any questions, please contact: CEServices@academycme.org
Copyright
© 2022. This CME-certified activity is held as copyrighted © by American Academy of CME and CheckRare CE. Through this notice, the Academy and CheckRare grant permission of its use for educational purposes only. These materials may not be used, in whole or in part, for any commercial purposes without prior permission in writing from the copyright owner(s).
Highlights on Pyruvate Kinase (PK) Deficiency from the 2021 American Society of Hematology Annual Meeting
Slides
Transcripts
Highlights on Pyruvate Kinase (PK) Deficiency from the 2021 ASH Annual Meeting - transcripts
Jointly Provided by
Supported by an educational grant from Agios Pharmaceuticals, Inc.
Start date: February 20, 2022
End date: March 31, 2023
Estimated time to complete: 0.25 hours
NO LONGER AVAILABLE FOR CREDIT
Activity Description
This accredited CME activity provides a summary of the latest information about Pyruvate kinase (PK) deficiency that was presented at the 2021 American Society of Hematology Annual Meeting (ASH 2021). Since the Covid-19 pandemic limited the ability for specialists to attend ASH 2021 and discuss this latest research, this program provides a review by Rachael Grace, MD, of the most clinically-relevant information on PK deficiency presented during the meeting.
PK deficiency is a rare genetic blood disorder characterized by low levels of the enzyme pyruvate kinase, which interrupts the glycolytic pathway causing hemolytic anemia. The degree of hemolysis is variable, ranging from mild forms of PK deficiency to life-threatening neonatal anemia that require exchange transfusions and subsequent continuous transfusion support. Both hematologists and generalists who may be involved in the care of patients with PK deficiency may benefit from learning the latest information about this rare disease, and its implications for patient care.
Activity Faculty
Rachael Grace, MD, MMSc
Associate Professor, Harvard Medical School
Director, Hematology Clinical Research Program
Dana-Farber/Boston Children’s Cancer and Blood Disorders Center
Boston, MA
Target Audience
This activity has been designed to meet the educational needs of physicians specializing in hematology and general medicine/pediatrics. Other members of the care team may also participate.
After participating in the activity, learners should be better able to:
- Describe the latest research to better manage people with PK deficiency and its clinical relevance
Accreditation and Credit Designation
In support of improving patient care, this activity has been planned and implemented by American Academy of CME, Inc. and CheckRare CE. American Academy of CME, Inc. is Jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physicians
American Academy of CME, Inc., designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Disclosure Statement
According to the disclosure policy of the Academy, all faculty, planning committee members, editors, managers and other individuals who are in a position to control content are required to disclose any relationships with any ineligible company(ies). The existence of these relationships is not viewed as implying bias or decreasing the value of the activity. Clinical content has been reviewed for fair balance and scientific objectivity, and all of the relevant financial relationships listed for these individuals have been mitigated.
Disclosures are as follows:
Faculty Educators
Dr. Grace discloses the following financial relationships:
- Advisory Board/Consultant: Agios, Principia
- Grant/Research Support: Agios, Dova, Novartis
Planners for this activity have no relevant financial relationships with any commercial interests.
This activity will review off-label or investigational information (RP-301).
The opinions expressed in this educational activity are those of the faculty, and do not represent those of the Academy or CheckRare CE. This activity is intended as a supplement to existing knowledge, published information, and practice guidelines. Learners should appraise the information presented critically, and draw conclusions only after careful consideration of all available scientific information.
Method of Participation
There are no fees to participate in the activity. Participants must review the activity information including the learning objectives and disclosure statements, as well as the content of the activity. To receive CME credit for your participation, please complete the pre and post-program assessments. Your certificate will be emailed to you in within 30 days.
Hardware/Software Requirements
Windows Requirements: • Operating system: Windows XP Service Pack 2 or later • Browser: Internet Explorer 7 or later, Mozilla Firefox 2.5 or later • Internet connection: DSL, cable modem, or other high-speed connection
Macintosh Requirements: • Operating system: Mac OS X v10.3 or later • Browser: Mozilla Firefox 2.5 or later • Internet connection: DSL, cable modem, or other high-speed connection
Privacy
For more information about the American Academy of CME privacy policy, please access http://www.academycme.org/privacy.htm. For more information about CheckRare's privacy policy, please access https://checkrare.com/privacy/
Contact
For any questions, please contact: CEServices@academycme.org
Copyright
© 2022. This CME-certified activity is held as copyrighted © by American Academy of CME and CheckRare CE. Through this notice, the Academy and CheckRare grant permission of its use for educational purposes only. These materials may not be used, in whole or in part, for any commercial purposes without prior permission in writing from the copyright owner(s).
