Gallia Levy, MD, PhD, Associate Group Medical Director, at Genentech explains why joint pain is so prevalent in persons with Hemophilia A.

Hemophilia A is a genetic disorder caused by missing or defective clotting protein, factor VIII. Symptoms are dependent on the level factor VIII present but in more severe cases, excessive bleeding can lead to severe pain, especially at joints.

Currently, most hemophilia A patients take a recombinant factor VIII product to control bleeding and numerous products are available, each with its own set of benefits and challenges.  Genentech produces Hemlibra (emicizumab-kxwh), a bispecific factor IXa- and factor X-directed antibody indicated for routine prophylaxis reduce bleeding episodes in persons with hemophilia A with or without factor VIII inhibitors.

To learn more about hemophilia and other rare bleed disorders, visit


  • Sign up
Lost your password? Please enter your username or email address. You will receive a link to create a new password via email.
We do not share your personal details with anyone.