Other Names: Multiple cartilaginous enchondroses; Dyschondroplasia; Enchondromatosis


Ollier Disease is a rare nonhereditary sporadic disorder where intraosseous benign cartilaginous tumors (enchondroma) develop close to growth plate cartilage. Prevalence of Ollier disease is about 1 in 100,000 people. The disease typically consists of multiple enchondromas which usually develop in childhood. The growth of these endochondromas usually stops after skeletal maturation. The affected extremity is shortened (asymmetric dwarfism) and sometimes bowed due to epiphyseal fusion anomalies. Individuals with Ollier disease are prone to breaking bones and often have swollen, aching limbs. On radiographs, streaks of low density are seen projecting through the diaphyses into the epiphyses of the long bones, due to ectopic cartilage deposits.


Contact the Genetic and Rare Diseases (GARD) Information Center for more information on Ollier Disease.



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