Rob Neville of Savara Pharmaceuticals provides an overview of his company’s Molgradex (for PAP and NTM lung infection) and AeroVanc (an inhaled formulation of vancomycin, for the treatment of persistent methicillin-resistant Staphylococcus aureus, or MRSA, lung infection in cystic fibrosis) programs.
Molgradex is an inhaled formulation of recombinant human GM-CSF that is being developed for the treatment of autoimmune pulmonary alveolar proteinosis, or PAP, a rare lung disease characterized by the build-up of lung surfactant in the alveoli, or air sacs, of the lungs. AeroVanc is an inhaled formulation of vancomycin, and is being developed for the treatment of persistent methicillin-resistant Staphylococcus aureus, or MRSA, lung infection in cystic fibrosis patients.