Kristin Highland, MD of the Cleveland Clinic explains the difference between the terms scleroderma and systemic sclerosis. 

Scleroderma is also an autoimmune condition that may visually appear to only impact the skin but often can involve other organs. When other organs are involved, systemic sclerosis is a more accurate description of the disease.

Systemic sclerosis is associated with immune dysregulation, microvascular damage, and organ fibrosis.  A common manifestation of systemic sclerosis is interstitial lung disease which is a leading cause of death in patients with systemic sclerosis. 

To learn more about this and other autoimmune conditions, visit