IgA Nephropathy

IgA nephropathy is an autoimmune kidney disorder characterized by settlement of immunoglobulin A (IgA), a protein that helps the body fight infections, in the kidneys. This leads to inflammation that makes it difficult for the kidneys to effectively filter blood,...

Gene Therapy For Hemophilia B

Brahm Goldstein, MD, Vice President, Research and Development, Hematology at CSL Behring, discusses HEMGENIX, a pivotal gene therapy for hemophilia B.     Hemophilia B is a bleeding disorder that slows the blood clotting process, caused by genetic changes in...

Synovial Sarcoma and Afami-cel

John Charlson, MD, Medical College of Wisconsin, discusses synovial sarcomas and the SPEARHEAD-1 clinical trial testing the safety and efficacy of afami-cel in this rare disease.     Synovial sarcoma is a cancer that can originate from different types of...