Arginine Vasopressin (AVP) Deficiency

Arginine vasopressin (AVP) deficiency is a rare neuroendocrine disorder caused by the loss or impaired function of vasopressinergic neurons in the hypothalamus and posterior pituitary gland. This results in impaired synthesis and secretion of AVP. A deficiency of AVP...

Pegcetacoplan in Patients With C3G and Primary IC-MPGN

Carla Nester, MD, professor at the University of Iowa and lead principal investigator for the VALIANT study, discusses the clinical trial testing pegcetacoplan in patients with C3G and primary IC-MPGN.     Complement 3 glomerulopathy (C3G) and immune-complex...