IgA Nephropathy

IgA nephropathy is an autoimmune kidney disorder characterized by settlement of immunoglobulin A (IgA), a protein that helps the body fight infections, in the kidneys. This leads to inflammation that makes it difficult for the kidneys to effectively filter blood,...

Gene Therapy For Hemophilia B

Brahm Goldstein, MD, Vice President, Research and Development, Hematology at CSL Behring, discusses HEMGENIX, a pivotal gene therapy for hemophilia B.     Hemophilia B is a bleeding disorder that slows the blood clotting process, caused by genetic changes in...

Synovial Sarcoma and Afami-cel

John Charlson, MD, Medical College of Wisconsin, discusses synovial sarcomas and the SPEARHEAD-1 clinical trial testing the safety and efficacy of afami-cel in this rare disease.     Synovial sarcoma is a cancer that can originate from different types of...

Eosinophilic Esophagitis (EoE)

Eosinophilic esophagitis (EoE) is a chronic autoimmune and digestive disorder in which large numbers of eosinophils, a type of white blood cell, are present in the esophagus. Eosinophils play a role in immune system regulation and fighting infections. Their...

The Canadian Fabry Association

Julia Alton, Executive Director at the Canadian Fabry Association, discusses the organization’s mission and their initiatives.     Fabry disease is a lysosomal storage disease characterized by insufficient alpha-galactosidase (alpha-GAL). The deficiency of...